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Standard goodness-of-fit plots for the final PK/PD model are available in Fig

This activation not only promotes mesangial cell proliferation and extracellular matrix deposition but also enhances NF-B nuclear translocation through phosphorylation, thereby sustaining inflammatory signaling cascades (31)

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Further specificity may be the noted special interaction with NO-system and NO-agents in various models and species [7,8,14] since BPC 157 induced the NO-release of its own [78,79]