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Currently, the majority of senolytics still cause damage to normal cells

doi: 10.1186/s12885-023-11324-0

2006;12:BR146153

The newly produced dimeric or oligomeric forms of IgA then enter the intestinal lumen via transcytosis and play an important role in mucosal defence against enteric pathogens (Brenchley and Douek 2012)

When this gets infected, inflamed, or ruptured, it can result in gastrointestinal bleeding

184 The results showed that the mean pain scores on a NRS decreased from 7.5 at 1 month to 2.9 at 12 months, and the RDQ decreased from 12.6 at 1 month to 2.8 at 12 months
