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Taken together, the above results suggest that decreased NO concentration promotes G6PD de-S-nitrosylation at C385 to increase its protein stability and activity (Fig

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Similar content being viewed by others Introduction Type 2 diabetes mellitus (T2DM) and obesity are becoming more and more common worldwide, a phenomenon which greatly increases morbidity and mortality from conditions like cancer and heart disease, among many others [1]

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Mitochondrial redox reactions are a major source of ROS in most cell types, including tumor cells

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10.1371/journal.pone.0057709 PLoS One 99 LinseisenJ.KimC

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Following transduction, cells were selected with 10 g/mL blasticidin (Sigma, SBR00022)

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Gubbels A, Spivack L, Lindheim SR, Bhagavath B

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