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JAMs, claudin, occludin, and tricellulin have been extensively studied and shown to be involved in TJ permeability in intestinal epithelial cells

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Disclosures Human subjects: Consent for treatment and open access publication was obtained or waived by all participants in this study

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Some experimental models indicate that GHK-Cu may regulate fibrosis-related gene pathways, suggesting a possible role in conditions involving abnormal tissue scarring