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Glioblastoma multiforme cells actively exploit the circadian clock to drive their malignant progression

There were promising signs of target engagement, providing grounds for further exploration of the mechanism Similar content being viewed by others Introduction Autonomic nervous system (ANS) imbalance, including increased sympathetic nervous system (SNS) activity and decreased parasympathetic nervous system (PNS) tone, is present in numerous cardiovascular diseases such as heart failure (HF) 1,2,3

A stereological study
Folia Med Cracov (2018) 58:11930
Hypoxia-preconditioned neural stem cell-derived exosomes enriched in CDC42 significantly downregulate ACSL4 expression in MPP + -stimulated human cerebral microvascular endothelial cells (HCMECs)
