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Chemical messengers, also known as signaling molecules, can be classified based on their function or chemical structure: There are 5 major classes of chemical messengers in the human body: There are four main types: glutamine, aspartate, glycine, and gamma aminobutyric acid (GABA)

Catechins found in green tea, such as epigallocatechin gallate (EGCG), have demonstrated protective effects against cardiovascular diseases These polyphenolic compounds exert antioxidant activity by scavenge ROS, chelate metal ions, and enhance the activity of endogenous antioxidant enzymes like catalase, superoxide dismutase (SOD) and glutathione peroxidase, thereby mitigate oxidative stress which is a contributor to cardiovascular pathology [179]

This process may ultimately affect the brains interoceptive network, particularly the insular cortex, resulting in altered perception and processing of signals related to fatigue and pain

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