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Lifespan extension is mediated by increased physiological levels of the HAAO substrate 3HAA

6-Phosphogluconolactonase is critical for the efficient functioning of the pentose phosphate pathway

Save the date Make plans to join us June 1821, 2027, for the 2027 Scientific Sessions at the Walter E

The observed reduction in HbA1c confirms the expected glycemic benefit of GLP-1 agonists, consistent with previous large-scale trials [16]

MOTS-c is a short peptide encoded within mitochondrial DNA

LRRK2 belongs to the ROCO protein family and contains multiple domains including a central catalytic region consisting of Ras-of-Complex (Roc) GTPase and serine/threonine-directed protein kinase domains separated by a C-terminal-of-Roc (COR) linker region [12, 13]