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Wnt/-catenin The Wnt/-catenin pathway plays a key role in glioma progression by maintaining tumor stem cell populations, inhibiting differentiation, and promoting invasion

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Tissue homogenates were centrifuged at 12,000 rpm at 4 C for 20 min and the supernatant was collected

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The variable interactions between CDK4/6 inhibitors and chemotherapeutic agents have also inspired another potential application for these inhibitors: the protection of hematopoietic stem cells and mitigation of chemotherapy-induced myelosuppression

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