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These calcium currents support autonomous pacemaking and also sustain an elevated spike rate after synaptic stimulation, facilitating the propagation of APs throughout the complex axonal terminals of SNc DA neurons (Pissadaki & Bolam, 2013

Mucin consists of a protein core of the prolinethreonineserine (PTS) sequences with tandem repeats and serine and threonine are extensively O -glycosylated

10.1136/bcr-2017-220928 256

However, intramuscular vitamin D injections have a much more immediate impact some patients report feeling the effects right away and because the vitamins are administered directly into the muscle, bypassing the gut, a much higher percentage of the vitamins can be utilised by the body

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