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As early as the 1930s, Western scholars applied it to treat leukemia, but the results were unsatisfactory
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doi: 10.1007/BF00225953 31 DodsonM
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On the other hand, many lactobacilli are not capable of producing folate de novo because some genes coding for enzymes involved in folate biosynthesis are lacking in their genome
Chen S, Wang S, Rong P, Liu J, Zhang H, Zhang J
