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52 The homology of both ligands, IGFs, and insulin is estimated to be at 50% which partially contributes to the cross-activation of IGF-1R and IR

It also reduces vascular remodelling and stiffness and improves arterial flexibility by suppressing vascular smooth muscle cell migration and proliferation as well as TGF--mediated fibrosis

In the endocrine system, H 2 S is mainly produced by three enzymes that catalyze different substrates

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An insight into anti-inflammatory effects of natural polysaccharides

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