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However, by limiting the gene deficiency only to mammary gland tissue using a Cre-LOX strategy, investigators were able to generate mouse models to study breast cancer in adults by overcoming the embryonic lethality associated with the original knockout line of mice (Xu 1999)

Serine and glycine can be mutually converted via hydroxymethyltransferases (cytosolic: SHMT1 and mitochondrial: SHMT2) [46]

Snchez-Gmez et al., 2010)

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Front Microbiol 9:
