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Significance was determined by one-way repeated measures analysis of variance, and the HolmSidak method for multiple comparisons versus the control group, using SigmaPlot 10.0 software (Systat Software, San Jose, CA, USA)

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But based on its fundamental mechanisms of actionits ability to drive blood flow to an avascular area, quell runaway inflammation, and provide the building blocks for new tissuethe scientific case is overwhelmingly compelling