l-carnitine supplement greece 650 L-Carnitine Tartrate 60caps (Warriorlab) -

Deadly conversations: nuclear-mitochondrial cross-talk

There's been a few

Soltani N, Qiu H, Aleksic M, Glinka Y, Zhao F, Liu R, Li Y, Zhang N, Chakrabarti R, Ng T, Jin T, Zhang H, Lu WY, Feng ZP, Prud'homme GJ, Wang Q

10.1128/mbio.02310-24 7 CalabreseC.PanuzzoC.StangaS.AndreaniG.RaveraS.MaglioneA.et al (2020)

This has inspired the use of pH-responsive elements to improve drug delivery to the brain

A pharmaceutical formulation comprising: an effective amount of cagrilintide and semaglutide, more than 10% w/v and less than 22% w/v, such as 10-20% w/v cyclodextrin of the hydroxypropyl-substituted alpha and/or beta type, said cyclodextrin comprising a minimum of about 0.4 and a maximum of about 1.0 hydroxypropyls per glucose unit, such as 0.58-1 .0 hydroxypropyls per glucose unit, about 3-30 mM histidine, about 10-40 mg/ml sorbitol, up to 2.0 mg/ml, such as up to 1 .5 mg/ml polysorbate 20 and/or 80, about 75-90% w/w water and having a pH of 5.6-6.0