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Description
NAD+ activates certain cellular receptors that cause temporary blood vessel dilation and smooth muscle relaxation, which can manifest as chest pressure, facial flushing, or a sensation of warmth spreading through the body

Keller passed away in 2009

DOI: 10.1080/15563650.2019.1606432 Aroda VR et al, "Long-term metformin use and vitamin B12 deficiency in the Diabetes Prevention Program Outcomes Study." Journal of Clinical Endocrinology and Metabolism, Feb

Avoid extreme temperatures
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