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Melatonin mitigates oxidative stress, inflammation processes, and cell apoptosis by upregulating the Nrf2 signaling pathway and downregulating COX-2 protein levels (135), as well as SOD, GPx, CAT, and Bcl-2 activities (136)

10.1007/s12035-023-03604-4 125 IsmailH.ShakkourZ.TabetM.AbdelhadyS.KobaisiA.AbediR.et al (2020)

However, B12 injections do not directly cause weight loss or significantly increase metabolism in people who already have adequate B12 levels

That said, proper storage away from light, air, and heat matters regardless of which form is used, adds Dr