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This differs from supplements like caffeine or creatine, which can directly enhance sports performance

Those are medical therapies under supervision and not directly comparable to a safe, over-the-counter oral ingredient

If you know you're not getting enough fiber like the vast majority of Americans a supplement like psyllium may be helpful for digestive regularity, but more research is needed to determine its benefits for weight loss

Gastric emptying can be assessed by ultrasonography which is a non-invasive technique that can be repeatedly performed because of its safety with good correlation to radionuclide estimates of gastric emptying 10

* very poor solubility in culture medium (drug precipitation) and toxicity against cells

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