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Thus, future trials must abandon systemic delivery in favor of targeted redox shielding of immune cells ex vivo (e.g., CAR-T engineering) before infusion

doi: 10.1016/j.plipres.2022.101165, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 61.Chvez-Castillo M, Ortega A, Cudris-Torres L, Duran P, Rojas M, Manzano A, et al

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Guggulsterone selectively modulates STAT-3, mTOR, and PPAR-gamma signaling in a methylmercury-exposed experimental neurotoxicity: Evidence from CSF, blood plasma, and brain samples