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(B) Western blotting showing cyto-c, cleaved caspase-9 and caspase-8 in the cytoplasm collected from four experimental groups

Here, we report for the first time an antioxidant function for LDHB in protecting KRAS -mutant lung cancer from ferroptosis, a ROS-dependent non-apoptotic cell death program triggered by iron- dependent accumulation of lipid peroxides in plasma membranes and intracellular organelles such as mitochondria [31]

Secondly, the cell proliferation phase is accompanied by the synthesis of a large number of extracellular matrix components

The control group mice received no treatment for the first four weeks

This includes areas where healing tends to drag on

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