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Of note, hemolysis is a fundamental feature of SCD and resulting excess hemin exposure 32 while hypoxia has been shown to induce the expression of fetal hemoglobin 33,34 , and promote the transition from expansion to differentiation during stress erythropoiesis 35

doi: 10.1186/s13046-024-02994-0 77 PengchengZQuanchengWZhibinLPeijunYKefengDRuohanZ

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Abstract N -acetylcysteine (NAC) is a medicine widely used to treat paracetamol overdose and as a mucolytic compound

Complete resolution remains the goal but may not always occur

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