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Best Practice: Apply copper peptides first and wait 1020 minutes before retinol, or use them on alternate nights depending on tolerance

The use of topical treatments should also be carefully assessed, as some topical agents have the probability of being absorbed systemically and causing unwanted side effects

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Martin-Sanchez D, Fontecha-Barriuso M, Sanchez-Nio MD et al (2018) Cell death-based approaches in treatment of the urinary tract-associated diseases: a fight for survival in the killing fields review-article

Degraded peptide may have lost its copper-binding capacity, creating a solution of free copper rather than beneficial GHK-CU complex

Wipe both vial stoppers with an alcohol swab