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212,213 The pathophysiological mechanism of GLP-1 in metabolic diseases GLP-1 plays a crucial role in the pathophysiology of metabolic diseases, particularly in T2DM and obesity

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Hi : HGF inhibitor (Rilotumumab/AMG102 is a human HGF-neutralising antibody from Amgen Inc., Thousand Oaks, CA, USA) 300 g in 200 l PBS IP twice weekly

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Mechanism: Both stimulate growth hormone release, but the DAC version has a longer half-life, allowing for less frequent dosing

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