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Studies have observed decreased cyclooxygenase-2 (COX-2) gene expression, reduced myeloperoxidase activity, and lower levels of pro-inflammatory cytokines including interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-)

They promote nerve regeneration by producing growth factors and ECM molecules, forming Bngner Bands, clearing debris, promoting new blood vessels, and differentiating into repair cells 53,54

Pacheco, R

doi: 10.1186/s12917-019-2227-8

When to See Your GP About B12 Symptoms Recognising when to seek medical attention for potential B12 deficiency is crucial for preventing irreversible complications, particularly neurological damage

Potential for stronger effect: Because the bioavailability (the fraction of the administered dose that reaches circulation) can be higher via injection, the impact on sleep architecture (e.g., slow-wave sleep increases) may be more pronounced