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The complete absence of human safety data for neurological applications, particularly long-term use affecting mental health, represents a critical knowledge gap

Meta-analysis of folic acid efficacy trials in stroke prevention: Insight into effect modifiers

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Each compound, with the exception of 1.65 , showed no cytotoxicity up to 3.25 mmolL 1 , and there was mostly over 100% cell viability on Caco-2, Fibroblast, and HT29-MTX-E12 cells at each tested concentration (as shown in Table 7)

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