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In experimental models, LC treatment improved food intake, reduced muscle mass loss, and led to the downregulation of atrogin-1 and MuRF1, biomarkers of skeletal muscle atrophy

While research on the relationship between ferroptosis and OA is limited, emerging evidence suggests that ferroptosis plays a crucial role in regulating chondrocyte activity, extracellular matrix degradation, and synovial inflammation, thereby influencing OA progression (Yao et al., 2021)

This, in turn, contributes to a reduction in antioxidant capacity

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[DOI] [PubMed] [Google Scholar] 148.Youseflu S., Sadatmahalleh S.J., Mottaghi A., Kazemnejad A

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