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Additionally, regulatory pathways such as Keap-Nrf2, Beclin-1 (BECN1), and ferritinophagy modulate ferroptosis dynamics, providing promising therapeutic targets

In this regard, small-molecule inhibitors of CXCR2 (e.g., AZD-5069, SCH527123) have entered clinical trials [119]

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In contrast, CBS, which produces H 2 S, did not increase the level of bound sulfane sulfur 26, 38, 39

Immediately following excision, tumour specimens were delivered to Surgical Pathology and reviewed by certified pathologists at the University of Rochester Medical Center, who allocated remnant malignant tissue for research