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PMID: 38432109 Sci Rep Chemotherapeutic hormesis induced by the tumor microenvironment in refractory ovarian cancer

Microbial exposure during early life has persistent effects on natural killer t cell function

Noticeably, synaptamide, a DHA metabolite analog of the endocannabinoid anandamide, ameliorates cAMP signaling and boosts the NSC differentiation impaired by ethanol (46) (Figure 2)

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This study specifically uncovers a non-canonical role of GSH metabolism within the BM microenvironment remodeled by peripheral inflammation

Notably, XPF-silenced cells displayed greater sensitivity to cisplatin treatment, similar to the cell viability observed for the normal cell line, IMR-90, as shown by the XTT cell viability assay and caspase-3 activation (Fig