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To the best of my knowledge, no specific nephrotoxicity has been reported in the many preclinical and current clinical trials [104]

10.1093/annonc/mdy001 52 RemonJ.SoriaJ.-C.PetersS.ESMO Guidelines Committee
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Inactivation of GPX4 leads to an accumulation of lipid peroxides, resulting in ferroptotic cell death
The gut-skin axis is a well-documented connection

doi: 10.1016/s0022-510x(97)00146-9
