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Ultimately, it leads to increased vascular permeability, defective angiogenesis, and activation of pro-inflammatory pathways, which finally hinders wound healing (Figure 6)

Loss of aqp4 polarized localization with loss of beta-dystroglycan immunoreactivity may induce brain edema following intracerebral hemorrhage

It is a small synthetic molecule that blocks an enzyme called NNMT (nicotinamide N-methyltransferase)

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However, this study has certain limitations that warrant further investigation

10.1016/s1074-7613(00)80562-2 Immunity