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For instance, deleting Pellino3 exacerbates insulin resistance by increasing pro-inflammatory macrophages, while inhibiting ITCH protects against steatohepatitis by promoting anti-inflammatory macrophages

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[DOI] [PubMed] [Google Scholar] 68.Checa-Rojas A., Delgadillo-Silva L.F., Velasco-Herrera M.D.C., Andrade-Dominguez A., Gil J., Santillan O., Lozano L., Toledo-Leyva A., Ramirez-Torres A., Talamas-Rohana P., et al

In diabetes research, it is used to investigate the pathogenesis of type 2 diabetes and validate potential therapeutic effects

[DOI] [PMC free article] [PubMed] [Google Scholar] 73.Quintero GC