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PET imaging of apoptosis with 64 Cu-labeled streptavidin following pretargeting of phosphatidylserine with biotinylated annexin-V

The authors reported that the risk of alcohol drinking relapse was lower in patients with an above-median initial blood concentration of nitric oxide metabolites and total antioxidant status

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Signaling pathways that regulate lipid metabolism play a crucial role in normal cellular and embryonic development

The peptide is unique among neuropeptides in several respects: it does not conform to typical neuropeptide structural motifs, its distribution in the brain and periphery differs from classical sleep-promoting substances, and it appears to exert effects through multiple pathways rather than through a single characterized receptor system

In addition, 2-oxoglutarate may also serve as a transcriptional modulator via activation of 2-oxoglutarate oxygenase, which has several biological roles, including demethylation of histones and nucleic acids, and destabilization of transcriptional factor HIF-1 42