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Repeated topical CAP application also impeded the progression of UVB-induced cutaneous squamous cell carcinoma in mice without damaging surrounding healthy tissue [206]

p-Value The probability that the observed result occurred by random chance alone

Important safety considerations regarding antioxidant use include: High-dose supplements are not risk-free Excessive vitamin E intake has been associated with increased mortality risk in some meta-analyses and may increase prostate cancer risk in men, though evidence remains debated Drug interactions Antioxidants can interact with medications including anticoagulants (vitamin E, coenzyme Q10), insulin and sulfonylureas (alpha-lipoic acid), and some herbal products may affect liver enzyme metabolism Quality concerns Supplements not registered under the MHRA Traditional Herbal Registration scheme are not subject to the same rigorous testing as licensed medicines

Chest 150 , 123130 (2016)

& Sagasti, A

Group 3 rats were administered LPS (100 g/kg b.w., i.p.)+GN (50 mg/kg b.w