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First, GBE may lead to increased blood flow by altering the blood viscosity and suppressing platelet-activating factors that can induce platelet aggregation, neutrophil degranulation, and ROS generation [37,38,39]

The clinical presentation of brain metastases encompasses a variety of neurological symptoms, primarily resulting from elevated intracranial pressure and the direct invasion of brain tissue by metastatic lesions [129]

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doi: 10.3233/JAD-160763

2022 Jan 19;23(3):1064.

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