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Our recently conducted preclinical studies in the penetrating TBI animal model, demonstrated zero toxic effects for IP-administered NACA at the highest concentration (600 mg/kg), supporting a safer profile for its use as a mitochondrial-targeted neuroprotection compound for TBI (unpublished data)

HIV-1 transgene expression in rats causes oxidant stress and alveolar epithelial barrier dysfunction

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Fukuda et al., 1994

To demonstrate the role of GSH in chemotherapy resistance, we analyzed transcriptomic data from chemotherapy patient samples in the GEO database and collected post-chemotherapy samples from patients who underwent neoadjuvant chemotherapy, assessing the expression levels of GSH and GSH synthesis-related antioxidant enzymes

L-serine is absorbed in the upper gastrointestinal tract, primarily in the small intestinal mucosa, while a significant portion of unabsorbed L-AA reaches the colon 7,8