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When activated by catecholamines like norepinephrine, they inhibit adenylyl cyclase, reducing cAMP and preventing fat breakdown

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Since autophagy is one of the main players in the degradation of damaged organelles and protein aggregates to maintain cellular homeostasis and is also tightly connected to other essential cellular signaling pathways like nutrient sensing or cell death, deregulation of this pathway can have severe consequences in cancer development and progression (199)

Temperature influences chemical kineticsthe rate at which chemical reactions occur
