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doi: 10.23736/S0390-5616.20.05107-3

These values, established in Erik M.P

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During the 7-day treatment schedule, MP-13 maintained stable antinociception without tolerance development, as evidenced by the unchanged microglial cell count in the periaqueductal gray, indicating that chronic exposure did not trigger neuroinflammatory adaptationa process in which microglia become activated, release pro-inflammatory cytokines, and contribute to opioid tolerance

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These treatments use different types of energy to stimulate collagen production and tighten the skin