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[DOI] [PubMed] [Google Scholar] 53.Aw T.Y

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Peripheral inflammatory signals pass through the damaged bloodbrain barrier and vagus nerve into the central nervous system, causing neuroinflammation [120]

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The most prevalent SP-D structure, the dodecameric conformation, seems to possess anti-inflammatory properties, while the trimeric or monomeric isoforms, are believed to have pro-inflammatory properties, when SP-D is in an inflammatory or more acidic environment (8691)

FEBS J 272:32823296 Passeri V, Koes R, Quattrocchio FM (2016) New challenges for the design of high value plant products: stabilization of anthocyanins in plant vacuoles