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It is also linked to cellular migration that helps move repair cells toward an injured area

Colorless Non-Ripening (CNR) is adversely controlled by APETALA2a ( AP2a) , a miR172 target that regulates fruit ripening through ethylene biosynthesis and signaling

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doi: 10.1126/science.aaz7548 199 WangWGreenMChoiJEGijnMKennedyPDJohnsonJKet al

AGEs are implicated in various pathophysiological mechanisms, including those associated with diabetic complications (cataracts, retinopathy, nephropathy, angiopathy), aging, and neurodegenerative disorders (Wautier and Guillausseau, 2001

Consequently, the mechanism of GLS1 action is more clearly defined, and the targeted inhibition of GLS1 has potential for use in cancer therapy