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These studies on the models have elucidated how this immune-mediated activation of the thyroid gland leads to systemic effects, such as the presence of goiter or the clinical symptoms of hyperthyroidism, which are weight loss, increased heart rate, and nervousness (Wmeau et al

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Topiramate does not affect the acquisition or expression of ethanol conditioned place preference in DBA/2J or C57BL/6J mice

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