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Defective check points and evasion of apoptosis allow the unregulated division of cancer cells (69)

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Expression of the DIO3 gene is highest the female uterus during pregnancy and in fetal and neonatal tissue suggesting a role for this enzyme in the regulation of thyroid hormone levels and functions during early development

Additionally, the ongoing Phase II trial (NCT04526899) combining BNT111 with cemiplimab has shown encouraging therapeutic outcomes [116]