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While proteasomes target and selectively degrade ubiquitinated proteins, autophagy degrades all the contents engulfed by autophagosomes, and, therefore, is called the bulk degradation system. In addition, selective autophagy pathways target cellular organelles, such as mitochondria and peroxisomes

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The ammonia that is produced elsewhere in the body, is usually detoxified by being converted to urea, which is then excreted

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