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Dodson M, Shakya A, Anandhan A, Chen J, Garcia JGN, Zhang DD

Preclinical and clinical studies have demonstrated a positive correlation between SARS-CoV-2 spike protein levels, induced by mRNA COVID-19 vaccination, and indices of glucose intolerance, insulin resistance, and serum TG levels

doi: 10.1007/s11033-020-05462-y

Nat Rev Psychol 1 , 694707 (2022)

Catalysis Mediated via Nucleophile Threonine Gamma-glutamyl transpeptidase enzyme catalyzes a two-step reaction, involving cleavage of -glutamyl bond present in -glutamyl compounds like glutathione and glutamine subsequently, followed by transfer of -glutamyl moiety to a water molecule or another amino acid or short peptide (Tate and Meister, 1981)

Other theories postulate that abnormalities in the enzymatic activity of aged retinal pigment epithelium (RPE) cells lead to the accumulation of metabolic byproducts