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These results are supported by studies demonstrating that p28 binds to the p53 DBD through non-polar residues at the interface, creating a short-range hydrophobic interaction

[DOI] [PubMed] [Google Scholar] 24.Van Sickle M.D., Duncan M., Kingsley P.J., Mouihate A., Urbani P., Mackie K., Stella N., Makriyannis A., Piomelli D., Davison J.S

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There is no solid scientific evidence linking it directly with mood regulation

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