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Homozygous or compound heterozygous mutations in LPL, apolipoprotein CII, apolipoprotein AV, GPIHBP1, and LMF are the causes of FCS

IL-28B is secreted primarily by dendritic cells (DCs) and macrophages and enhances viral clearance by promoting robust CD8 + T cell responses while reducing regulatory T cell (T reg )-mediated suppression (112)
Thiele JR, Habersberger J, Braig D, Schmidt Y, Goerendt K, Maurer V, Bannasch H, Scheichl A, Woollard KJ, von Dobschutz E, et al

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The longitudinal study shows losses of 11.8% per decade in womens knee extensor strength and 17.4% per decade in flexor strength [59]
10.1016/j.nut.2020.110856 16