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Description
This is primarily done by analyzing the Amide I band (around 1600-1700 cm -1 originating from the C=O stretching and N-H in-phase bending vibration of the amide group), which is sensitive to protein secondary structure due to the variations in hydrogen bonding and dipole-dipole interactions within -helices, -sheets, and disordered regions (Sutherland, 1952

10.1161/CIRCULATIONAHA.106.179918

Rev Endocr Metab Disord 2008;9:203-11

Methods Enzymol 352: 258268
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Inhibiting 3HSD1 to eliminate the oncogenic effects of progesterone in prostate cancer
