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We hypothesized that driven by SMs amphiphilicity, SMPTX conjugates will self-assemble into nanovesicles, with PTX securely packaged in a lipid bilayer, which would improve PK and tumor uptake, and diminish systemic toxicities compared to nonconjugated PTX, thereby boosting anticancer efficacy

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This matters for cardiovascular risk assessment and is one reason some researchers switch between medications based on their specific metabolic goals and side effect tolerance

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The intensity of Giemsa staining is correlated with genomic features