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Some hemoglobin inevitably escapes from phagocytes, which leads to variable decreases in plasma haptoglobin, an 2 -globulin that binds free hemoglobin and prevents its excretion in the urine

Oxygen availability and metabolic adaptations

For instance, recent studies in mouse models have revealed that astrocytes maintain an intracellular lactate reservoir that can be rapidly mobilized in response to neuronal cues such as elevated extracellular K + or membrane depolarization

V.FischbachL.GisbertJ

The recently proposed model of MMP-2 interacting with CTX (Othman et al., 2017) shows that residues 2936 (which correspond to CTX-4) are directly involved in the interaction with MMP-2 (Othman et al., 2017)

doi: 10.1210/en.2008-0345 67 OuyangQ.XuY.BanY.LiJ.CaiY.WuB.et al