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In the outer nuclear layer (ONL), pathological changes manifested as edema and an increase in the space between the photoreceptor nuclei were noted
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10.1080/0886022X.2021.1994995 43

Moreover, curbing LAT1 or its complete absence can diminish the proliferation of T cells incited by IL-23/IL-1 and curtail the secretion of IL-17/IL-22, leading to protection against IMQ-induced inflammation (115)

For instance, neurons have high energy demands, and mtDNA damage in the CNS contributes to HIV-associated neurocognitive disorders (HAND) through neuronal energy failure and neuroinflammation (9195)
