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The indispensable role of the C terminal domain in preventing fibrillation has been demonstrated by an engineered -synuclein with truncated C terminus which not only displayed accelerated fibrillation kinetics but also promoted the phase separation of WT -synuclein (Huang et al., 2022)

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In vivo studies were then carried out with the BT474 xenografted mice treated with MAHNP-Dox, free Dox, or saline

All TUEs for cannabis or other FDA-approved cannabinoid medications (e.g., Marinol, dronabinol) must meet the criteria set forth in the International Standard for TUEs in order to be approved

Placebo Group Group participants received quarterly group lifestyle change classes throughout the study

doi: 10.1128/IAI.00685-19 66 Gray-OwenS