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The textbooks describe a fairly distinctive profile: Most often diagnosed in the fifth to seventh decades of life (50s-70s), with a wide range across all adult ages

The prevalence of pruritus varies depending on the underlying cause, with reports indicating rates of up to 70% in primary biliary cholangitis, 2.530% in chronic hepatitis C virus-related liver disease, and roughly 8% in cirrhosis attributed to hepatitis B virus infection (20)

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It plays a fundamental role in energy production by acting as a transport vehicle for fatty acids